Scepticism regarding the quality and predictiveness of modern science has finally arrived in the lay press. This week The Economist has devoted its issue, including, cover, editorial, and leader to what they call ‘unreliable research’. Even closer to home, this weeks New Scientist (also with cover, editorial and leader) turns on neuroscience, with a similar message and material, and the bottom line that ‘the vast majority of brain research is now drowning in uncertainty.’ A clear signal that it is either time to abandon ship, or to clean up the mess!